Sodium Sulphobutylether

Basic Info.

Model NO.	food grade
M F	C42h70o35
En No.	1308068-626-2
M G	1134.9842
CAS No.	182410-00-0
Store	Dry and Cool Place
Transport Package	25kg/Drum
Specification	BP/USP/FCC
Trademark	JK
Origin	China
HS Code	294000
Production Capacity	100mt/Year

Product Description

Betadex Sulfobutyl Ether Sodium is a sodium salt produced when betacyclodextrin is alkylated by 1,4-butanesulfonic acid lactone under alkaline conditions. It is an anion, highly water-soluble betacyclodextrin derivative. Betadex Sulfobutyl Ether Sodium is can be well combined with the drug molecules to form non-covalent complex, thereby enhancing the stability, water solubility, and safety of the drug, reducing its renal toxicity, easing drug hemolysis, controlling drug release rate, covering bad smell, etc. Compared with betacyclodextrin, sulfobutyl betacyclodextrin sodium has a higher water solubility, smaller hemolytic effect, and lower renal toxicity, which make it a new pharmaceutical excipient with very broad application prospects.

Betadex Sulfobutyl Ether Sodium ( EP9.6)
CONTENT
SULFOBUTYLBETADEX SODIUM	98.0%-102.0%
AVERAGE DEGREE OF SUBSTITUTION	5.9-6.6
CHARACTERS
APPEARANCE	white or almost white, hygroscopic powder
SOLUBILITY	freely soluble in water, practically insoluble in anhydrous ethanol and in methylene chloride
IDENTIFICATION
A INFRAED ABSORPTION SPECTROPHOTOMETRY	same absorption bands. the relative intensity of some absorption bands may vary.
B SODIUM REACTION	it gives reaction (a) of sodium
TEST
PH	5.0-7.5
APPEARANCE OF SOLUTION	clear and colorless
REDUCING SUGARS	NMT 0.05%
IMPURITIES
Limit of betadex	NMT 0.1%
Limit of 1'2λ6-oxathiane-2,2-dione	NMT 0. 5ppm
Limit of 4-hydroxybutane-1-sulfonic acid	NMT 0. 1%
Limit of 4,4'-oxydi(butane-1-sulfonic acid)	NMT 0. 05%
LIMIT OF SODIUM CHLORIDE	NMT 0.20%
WATER	NMT10.0%
MICROBIAL CONTAMINATION
the total aerobic microbial count	NMT 100cfu/g
the total combined molds and yeasts count	NMT 100cfu/g
Escherichia coli.	absence
Salmonella	absence

Natural Cyclodextrin;
Alpha-Cyclodextrin	Beta-Cyclodextrin		Gamma-Cyclodextrin
Alpha Cyclodextrin Derivatives;
Hydroxypropyl-Alpha-Cyclodextrin		Sulfobutylether-Alpha-Cyclodextrin
Beta Cyclodextrin Derivatives;
Hydroxypropyl-Beta-Cyclodextrin		Sulfobutyl ether-Beta-Cyclodextrin Sodium
Piroxicam-Beta-Cyclodextrin		Glucosyl-Beta-Cyclodextrin
Hydroxyethyl-Beta-Cyclodextrin		Carboxymethyl-Beta-Cyclodextrin
Hydroxypropyl-Beta-Cyclodextrin		2,6-Dimethyl-Beta-Cyclodextrin
2-Hydroxypropyl-Beta-Cyclodextrin		Methyl-Beta-Cyclodextrin
Gamma Cyclodextrin Derivatives;
Hydroxypropyl-Gamma-Cyclodextrin		Sulfobutylether-Gamma-Cyclodextrin
Cyclodextrin Inclusion Compounds
Soluble inclusion compound of pueraria flavones		Soluble inclusion compound of Gynostemma Extract
Plant essential oil inclusion compound		Flavor inclusion compound
Rotation substance separation reagent
Chromatogram filler: cyclodextrins.

β-Cyclodextrin, sulfobutyl ethers, sodium salts Basic information

Product Name:	β-Cyclodextrin, sulfobutyl ethers, sodium salts
Synonyms:	CAPTISOL;Sodium sulfobutylether β-cyclodextrin;Betadex Sulfobutyl Ether Sodium (500 mg);sulfobutyl ether B-cyclodextrin;sodiuM salts;sulfobutyl ethers;SodiuM Sulphobutylether-β-Cyclodextrin;CAPTISOL,BETA-CYCLODEXTRIN SULFOBUTYL ETHERS, SODIUM SALT
CAS:	182410-00-0
MF:	C42H70O35
MW:	1134.9842
EINECS:	1308068-626-2
Product Categories:
Mol File:	182410-00-0.mol

β-Cyclodextrin, sulfobutyl ethers, sodium salts Chemical Properties

solubility	Soluble in water. Insoluble in acetone, methanol, chloroform.
form	Solid powder
color	White to off white

Safety Information

HS Code

2940006000

MSDS Information

β-Cyclodextrin, sulfobutyl ethers, sodium salts Usage And Synthesis

Hunan JK International Trade Corporation / JK BIO-CHEM CO.,LTD is a professional exporter of food/feed additives and food /feed ingredients in China. With years of development, now we are able to provide the following food additives and food ingredients: thickeners, antioxidants, preservatives, vitamins, sweeteners, proteins, acidulants, nutritional supplements, flavours, coenzyme and so on.
Our food additives and food ingredients, especially our Ascorbic Acid (Vitamin C), Acesulfame-K, Aspartame, Citrates, Dextrose, D-Xylose, Erythorbic Acid, Fumaric Acid, Fructose,Maltodextrin, Malic Acid, Monosodium glutamate, Lactic Acid Potassium Sorbate, Sodium Erythorbate, Sodium Cyclamate, Sodium Saccharin, sodium benzoate, Sodium ascorbate, Sorbic Acid, xanthan Gum, Xylitol, Tartaric Acid, I+G, , Vanillin, Sucralose, Stevia and so on, have been exported to more than 60 countries for our good quality products.
Our staff of sales and technical support is available to help you in selecting the right protection for your application as well as to provide you with samples of our products for evaluation. At High Five, we are committed to providing the highest level of customer service, competitive pricing, speedy delivery and a comprehensive, cutting-edge product offering. Our ultimate goal is your satisfaction.

Packing&Shipping
FAQ
Q1.What's the payment terms?We could accept T/T, L/C, DP payment terms.Q2.How about the different index of products in same application?Specifications can be customized according to your application.Q3.How about the samples of products?We can provide free samples under 2Kg(not including freight charge).Q4.How about the price of products?Our products are chemical synthesis got from underground brine, which is available for a variety of usage. Our products are high purity with good quality, and the price is based on different specification and quantity.Q5.What's the shelf life for the cargoes?Our product's shelf life is 2 years, which is based on dry and ventilated storage.Q6.What's the package of the cargoes?20kg/25kg woven bags, within plastic bags, or as customized.Q7.What's the delivery time?We usually deliver the cargoes within 10~20 days after receiving customer's payment or original L/C.Q8.Which documents can we supply?Commercial Invoice, Packing List, Certificate of Analysis, Certificate of Origin (FORM E), Bill of Loading, ISO etc.The documents will be sent by Express within 24 hours against your full payment.Q9.Why do you choose us?We accept safe and diversified payment terms.We supply a price trend to ensure clients know marketing information in time. We will take charge of 100% responsibility forquality issue. We strive to create value for each customer we serve by meeting their unique needs and providing solutions to solve their problems and achieve their objectives.